The following are my colleagues and fellow scientists who I have collaborated with, and the titles of our first collaborative research paper. Most of them have become top researchers/scientists in their fields and are still active in the front lines. Here, I would like to introduce those who have become professors in their affiliations in Japan.

Professor Koji Kawahito

(Division of Cardiovascular Surgery, Department of Surgery, Jichi Medical University) :

Kawahito K, Kobayashi E, Misawa Y, Adachi H, Fujimura A, Ino T, Fuse K.: Recovery from lymphocytopenia and prognosis after adult extracorporeal membrane oxygenation. Arch Surg. 1998 Feb;133(2):216-7.

Professor Yoji Hakamata

(Nippon Medical School; Nippon Veterinary and Life Science University):

Hakamata Y, Tahara K, Uchida H, Sakuma Y, Nakamura M, Kume A, Murakami T, Takahashi M, Takahashi R, Hirabayashi M, Ueda M, Miyoshi I, Kasai N, Kobayashi E.: Green fluorescent protein-transgenic rat: a tool for organ transplantaion research. Biochem Biophys Res Commun. 2001; 286(4):779-785.

Professor Yoshinori Hosoya

(Department of Gastrointestinal Surgery, Jichi Medical University)

Hosoya Y, Kitoh Y, Kobayashi E, Okabe R, Fujimura A, Kanazawa K.: Combination effects of tamoxifen plus 5-fluorouracil on gastric cancer cell lines in vitro. Cancer Lett. 1999 Jun 1;140(1-2):139-43

Professor Hisanaga Horie

(Department of Surgery, Division of Gastroenterological, General and Transplant Surgery, Jichi Medical University):

Horie H, Kanazawa K, Kobayashi E, Okada M, Fujimura A, Yamagiwa S, Abo T.:Effect of intestinal bacteria on the development of colonic neoplasm II. Changes in the immunological environment. Eur J Cancer Prev. 1999; 8(6):533-537.

Professor Yasuo Hozumi

(Department of Breast Surgery, University of Tsukuba Hospital/ Ibaraki Prefectural Central Hospital):

Hozumi Y, Kobayashi E, Miyata M, Fujimura A.: Immunotherapy for experimental rat autoimmune thyroiditis using a novel immunosuppressant, FTY720. Life Sci. 1999; 65(17): 1739-1745.

Professor Sadahiko Iwamoto

(Department of Human Genetics, Center for Molecular Medicine, Jichi Medical University):

Iwamoto S, Kumada M, Kanesaki T, Okuda H, Kajii E, Inagaki T, Saikawa D, Takeuchi K, Ohgawara S, Takahashi R, Ueda S, Inoure S, Tahara K, Hakamata Y, Kobayashi E.: Rat encodes paralogous gene equivalent of human histo-blood group ABO gene: association with antigen expression by overexpression of Human ABO transferase. J Biol Chem. 2002; 277(48):46463-46469.

Professor Koichi Mizuta

(Saitama Children’s Medical Center):

Mizuta K, Hishikawa S, Yoshida T, Kobayashi E, Uchida H, Fujimura A, Kawaraasaki H, Hashizume K.: Survival of rats undergoing continuous bile drainage dependents upon maintenance of circadian rhythm of bile secretion. Chronobiol Int. 1999; 16(6):759-765.

Professor Takashi Murakami

(Department of Microbiology, Saitama Medical University):

Murakami T, Inoue S, Sato Y, Ajiki T, Ohsawa I, Kobayashi E.: Genetic modification in organ transplantation and in vivo luciferase imaging. Progress in Biomedical Optics and Imaging. 2005; 6(19): 169-176.

Professor Atsunori Nakao

(Graduate School of Medicine Dentistry and Pharmaceutical Sciences, Medical School, Okayama University):

Nakao A, Mitsuoka N, Shen SD, Tanaka N, Kobayashi E.:Rat small intestinal transplantation: a comparison of the cuff and hand-suture methods. Acta Med Okayama. 2000 Dec;54(6):259-64

Professor Takashi Okada

(Center for Gene and Cell Therapy, Institute of Medical Science, The University of Tokyo):

Okada T, Uchibori R, Iwata-Okada M, Takahashi M, Nomoto T, Nonaka-Sarukawa M, Ito T, Liu Y, Mizukami H, Kume A, Kobayashi E, Ozawa K.:A histone deacetylase inhibitor enhances recombinant adeno-associated virus-mediated gene expression in tumor cells.Mol Ther. 2006 Apr;13(4):738-46. Epub 2006 Jan 4.

Professor Ichiro Sekiya

(Section of Applied Regenerative Medicine, Tokyo Medical and Dental University):

Horie M, Sekiya I, Muneta T, Ichinose S, Matsumoto K, Saito H, Murakami T, Kobayashi E.:Intra-articular Injected synovial stem cells differentiate into meniscal cells directly and promote meniscal regeneration without mobilization to distant organs in rat massive meniscal defect.Stem Cells. 2009 Apr;27(4):878-87. doi: 10.1634/stemcells.2008-0616

Professor Tatsuya Shimizu

(Institute of Advanced Biomedical Engineering and Science, Tokyo Women’s Medical University) :

Shimizu T, Sekine H, Yang J, Isoi Y, Yamato M, Kikuchi A, Kobayashi E, Okano T.: Polysurgery of cell sheet grafts overcomes diffusion limits to produce thick, vascularized myocardial tissues. FASEB J. 2006; 20(6):708-710.

Professor Masafumi Takahashi

(Division of Inflammation Research, Center for Molecular Medicine, Jichi Medical University):

Takahashi M, Nishihira J, Shimpo M, Mizue Y, Ueno S, Mano H, Kobayashi E, Ikeda U, Shimada K.: Macrophage migration inhibitory factor as a redox-sensitive cytokine in cardiac myocytes. Cardiovas Res. 2001; 52(3):438-445.

Professor Hideto To

(Department of Medical Pharmaceutics, University of Toyama):

To H, Xiu DR, Hishikawa S, Uchida H, Sudou T, Sunada K, Sugimoto K, HiguchiS, Fujimura A, Kobayashi E.: Dosing time-dependent pharmacological effectsof anti-metabolites for rat cardiac graft. Res Commun Mol Pathol Pharmacol.2001; 110(5-6):319-332.

Professor Nobuyuki Toyama

(Omiya Medica Center, Jichi Medical University):

Toyama N, Kobayashi E, Kamada N, Doy M, Miyata M.: Samll bowel transplantation in rats: Endoscopic and histological evaluation of graft rejection. Gastroenterologia Japonica. 1993; 28(2): 209-217.

Professor Hiroo Uchida

(Department of Pediatric Surgery, Nagoya University Graduate School of Medicine):

Uchida H, Tanaka H, Kito Y, Yanagisawa K, To H, Tago K, Mizuta K, Fujimura A, Tominaga S, Hashizume K, Kobayashi E.: Mechanisms of Immuromodulation induced by blood transfusion: Identification of Humoral factors. Transplant Proc. 2000; 32(2): 255-256

Professor Takashi Yokoo

(Division of Nephrology and Hypertension, Department of Internal Medicine, The Jikei University School of Medicine):

Yokoo T, Fukui A, Ohashi T, Miyazaki Y, Utsunomiya Y, Kawamura T, Hosoya T, Okabe M, Kobayashi E.: Xenobiotic kidney organogenesis from human mesenchymal stem cells using a growing rodent embryo. J Am Soc Nephrol. 2006; 17(4):1026-1034.

Professor Hiroyuki Yoshino

(Gunma University):

Yoshino H, Hashizume K, Kobayashi E.: Naked plasmid DNA transfer to the porcine liver using rapid injection with large volume. Gene Ther. 2006; 13(24):1696-1702.

Professor Jun Fujishiro

(Department of Pediatric Surgery, The University of Tokyo Hospital):

Fujishiro J, Tahara K, Inoue S, Kaneko T, Kaneko M, Hashizume K, Kobayashi E.: Immunologic benefits of longer graft in rat allogenic small bowel transplantation. Transplantation. 2005 Jan 27;79(2):190-5.

Professor Yasunaru Sakuma

(Department of Surgery, Division of Gastroenterological, General and Transplant Surgery, Jichi Medical University):

Sakuma Y, Uchida H, Nagai H, Kobayashi E. High-dose tacrolimus and lengthy survival of the combined rat pancreas/spleen graft in a high-responder combination. Transpl Immunol . 2001 Oct;9(1):37-42.

Professor Shintaro Yagi

(Faculty of Medicine, Institute of Medical, Pharmaceutical and Health Sciences Department of Hepato-Biliary-Pancreatic Surgery and Transplantation/Pediatric Surgery):

Yagi S, Doorschodt BM, Afify M, Klinge U, Kobayashi E, Uemoto S, Tolba RH. Improved preservation and microcirculation with POLYSOL after partial liver transplantation in rats. J Surg Res. 2011 May 15;167(2):e375-83. doi: 10.1016/j.jss.2010.12.040. Epub 2011 Jan 31.